Monobaktamy, antibiotics,

monobactams (ATC J 01 DF) - a group of ÃŽË›-lactam antibiotics with a single ring of bactericidal . Its mechanism of action by blocking the activity of transpeptid ase PBP involved in the final stage of the synthesis of bacterial cell walls peptydoglikanu. Representatives of the monobactams are, among others.: Aztreonam, karumonam. Aztreonam bactericidal activity only against aerobic bacteria in G (eg, Neisseria, Pseudomonas). Is resistant to ÃŽË›-lactamase gram negative bacteria.